Medicube Hyaluronic Multi Peptide PDRN Serum 30ml

Description

The MEDICUBE Hyaluronic Multi Peptide PDRN Serum is a 30ml two-layer face serum that separates in the bottle and has to be shaken before every use. That single detail tells you most of what you need to know about it: this is not a thin watery hydrator, it is a hydrating layer and an oil layer that you mix yourself at the moment of application. Below is a full, honest breakdown of what is inside the bottle, where each headline ingredient actually sits on the ingredient list, who this suits, who it does not suit, and how to fit it into a routine in Bangladesh weather.

Table of contents

Use this table of contents to jump through the Hyaluronic Multi Peptide PDRN Serum guide.

• What the Hyaluronic Multi Peptide PDRN Serum is
• The two layers, and why shaking matters
• Full ingredient positions, counted
• Where the peptides in the Hyaluronic Multi Peptide PDRN Serum really sit
• The hyaluronic acid story is real, with a caveat
• PDRN, and what “salmon DNA” means on a label
• Bergamot oil at 27th in the Hyaluronic Multi Peptide PDRN Serum
• Who the Hyaluronic Multi Peptide PDRN Serum suits
• Who should think twice
• How to use the Hyaluronic Multi Peptide PDRN Serum
• Layering it with the rest of your shelf
• What the Hyaluronic Multi Peptide PDRN Serum feels like

What the Hyaluronic Multi Peptide PDRN Serum is

The Hyaluronic Multi Peptide PDRN Serum is a 30ml (1.01 fl oz) leave-on serum from MEDICUBE, the Korean skincare brand. The front of the bottle carries two printed figures: Sodium Hyaluronate 0.5% and 13 Types Peptide. Both of those are the brand’s own on-pack statements, and both are supported by the ingredient list, which we have counted position by position further down this page. The full formula runs to 53 ingredients.

The two layers, and why shaking matters

Left standing, the Hyaluronic Multi Peptide PDRN Serum bottle settles into a clear upper layer and a blue-tinted lower layer. The oil phase comes mainly from neopentyl glycol dicaprate, which sits 2nd on the ingredient list, plus squalane at 22nd and jojoba seed oil at 30th. If you pipette straight out of an unshaken bottle you will get an unpredictable ratio of the two phases — sometimes mostly oil, sometimes mostly water. MEDICUBE’s own instruction is explicit about this, and we repeat it in the directions section because it changes how the Hyaluronic Multi Peptide PDRN Serum feels on skin more than any other step.

Full ingredient positions, counted

We counted every one of the 53 ingredients in the Hyaluronic Multi Peptide PDRN Serum so you are not guessing. Here is where the ones people actually buy this for land:

• Niacinamide — 6th of 53. The highest-placed active in the formula.
• Sodium hyaluronate — 10th of 53. This is the 0.5% the label refers to.
• Panthenol — 12th. Humectant and soothing agent.
• Allantoin — 14th. Soothing.
• Adenosine — 15th. A Korean-regulated functional anti-wrinkle ingredient.
• Alpha-arbutin — 21st. Tone-related.
• Squalane — 22nd. Part of the oil phase.
• Sodium DNA — 25th. This is the PDRN-family ingredient.
• Bergamot fruit oil — 27th. See the caution section below.
• The 13 peptides — 33rd to 46th. Every single one.
• Six further hyaluronic acid forms — 47th to 53rd.

Where the peptides in the Hyaluronic Multi Peptide PDRN Serum really sit

This is the part most listings skip. The product is named after its peptides, and there genuinely are 13 of them: acetyl hexapeptide-8, acetyl tetrapeptide-3, arginine/lysine polypeptide, copper tripeptide-1, dipeptide-2, hexapeptide-11, nonapeptide-1, oligopeptide-1, palmitoyl hexapeptide-12, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1 and tripeptide-1. The count on the label is accurate.

What the label does not tell you is that all 13 sit between positions 33 and 46 of 53. Ingredient lists are ordered by weight down to 1%, and everything below that threshold can be listed in any order. Peptides are active at low percentages, so their position is not automatically a problem — but it does mean the peptide content here is a low-percentage blend, not the headline volume of the formula. Anyone telling you otherwise is selling, not counting. We would rather you buy the Hyaluronic Multi Peptide PDRN Serum knowing exactly that.

The hyaluronic acid story is real, with a caveat

There are eight distinct hyaluronic acid derivatives in the Hyaluronic Multi Peptide PDRN Serum: sodium hyaluronate (10th), sodium hyaluronate crosspolymer (28th), then hyaluronic acid, hydrolyzed hyaluronic acid, hydrolyzed sodium hyaluronate, hydroxypropyltrimonium hyaluronate, potassium hyaluronate and sodium acetylated hyaluronate clustered at 47th to 53rd. Different molecular weights sit at different depths in the skin’s surface layers, so a blend is a reasonable formulation choice rather than a gimmick. But seven of the eight are at the tail of the list. The one doing the heavy lifting is the sodium hyaluronate at 10th — the 0.5% on the label.

PDRN, and what “salmon DNA” means on a label

PDRN stands for polydeoxyribonucleotide. On a cosmetic ingredient list it appears as sodium DNA, and in the Hyaluronic Multi Peptide PDRN Serum that sits 25th of 53. MEDICUBE markets it under the salmon PDRN name. In injectable medical use PDRN has a body of clinical literature behind it; in a topical leave-on cosmetic, the molecule is far larger than what passes easily through intact skin, and the evidence base is much thinner. We are not going to tell you it does what the injectable does. It is in the formula, it is at 25th place, and that is the honest position.

Bergamot oil at 27th in the Hyaluronic Multi Peptide PDRN Serum

Citrus aurantium bergamia (bergamot) fruit oil is 27th of 53. Untreated bergamot oil contains bergapten, a furocoumarin that is phototoxic — it can cause a burn-like reaction on sun-exposed skin. Cosmetic-grade bergamot used in leave-on products is normally furocoumarin-free (FCF), and EU cosmetic rules cap furocoumarin content. MEDICUBE does not state on the packaging or product page which grade it uses.

We are not claiming this product is phototoxic. We have no basis to say that, and the overwhelming likelihood is that a major Korean brand is using the treated grade. What we are saying is that the information is not published, the ingredient is present, and the sensible response is the one you should be following anyway: use a broad-spectrum sunscreen every morning. If you have a known citrus sensitivity or you react to fragranced oils, patch test the Hyaluronic Multi Peptide PDRN Serum on your inner forearm for three days before putting it on your face.

Who the Hyaluronic Multi Peptide PDRN Serum suits

MEDICUBE lists this for combination, dry and oily skin, targeting dryness, dehydration and loss of elasticity. In practice the oil phase makes it a better fit for normal, combination and dehydrated skin than for very oily or actively congested skin. Dry skin will likely want a cream over the top. The niacinamide at 6th and the panthenol at 12th give it a reasonable barrier-support profile, and the allantoin at 14th keeps it fairly calm.

Who should think twice

If you are extremely oily and breakout-prone, an oil-phase serum with jojoba and squalane may be more than you want mid-routine. If you have a citrus or essential-oil sensitivity, the bergamot at 27th is a real consideration. If you are pregnant or nursing, or you are already on a prescription topical, run the ingredient list past your doctor rather than taking a product page’s word for it. And if you are looking for a single-ingredient, high-percentage active, this is the wrong category — the Hyaluronic Multi Peptide PDRN Serum is a broad multi-ingredient hydrator, not a targeted treatment.

How to use the Hyaluronic Multi Peptide PDRN Serum

MEDICUBE’s own directions: after cleansing, shake the serum before use to mix the oil layer and the serum layer well. Apply an appropriate amount to the skin and gently pat for absorption.

In a full routine that means: cleanse, tone if you use one, shake the bottle for three to five seconds, dispense two to three drops, press it into damp skin with your palms rather than rubbing, wait about a minute, then moisturiser. Morning only, evening only or twice daily all work. Sunscreen is non-negotiable in the morning.

Layering it with the rest of your shelf

The Hyaluronic Multi Peptide PDRN Serum layers cleanly under most creams and over most toners. Keep it away from a strong direct-acid step in the same sitting — if you use an AHA, BHA or high-strength vitamin C, put them on alternate nights or alternate ends of the day rather than stacking them. With retinol, apply the serum first and the retinol on top, or run them on alternate evenings while your skin adjusts. If you want a toner underneath it, the MEDICUBE PDRN Pink Niacinamide Milky Toner 150ml pairs well.

What the Hyaluronic Multi Peptide PDRN Serum feels like

Shaken, it goes on as a light emulsion with a slight slip from the oil phase, and it settles without a heavy film. Unshaken and oil-heavy, it will feel greasy — which is exactly the complaint you see from people who did not read the instruction. Two to three drops covers the face. More than that and you will be sitting in it.

Using it in Bangladesh humidity

Dhaka’s humidity changes how every serum behaves. During the monsoon and through the hot months, two drops of the Hyaluronic Multi Peptide PDRN Serum under a gel moisturiser is usually enough; humectants pull moisture from the air and you do not need to force it. In the drier winter weeks from December through February the same serum under a richer cream makes a lot more sense, because the humectants have less ambient moisture to draw on and need something occlusive above them to hold water in.

Storing your Hyaluronic Multi Peptide PDRN Serum

Keep the Hyaluronic Multi Peptide PDRN Serum upright, capped, out of direct sunlight, and away from a hot windowsill or a bathroom shelf that sits above a shower. Oil-containing formulas do not enjoy heat cycling. Room temperature in a cupboard is fine; a fridge is unnecessary.

What we will not claim

We will not tell you this erases wrinkles, replaces a clinic treatment, or delivers injectable-level PDRN results through intact skin. We will not quote a moisture-retention percentage as though it were an independent finding. What we will tell you is what is in the bottle, in what order, at what stated concentration, and what that reasonably supports: hydration, barrier support from the niacinamide and panthenol, and a low-percentage peptide blend.

Fragrance and preservative notes

There is no “parfum/fragrance” entry on the list. The scent comes from the bergamot fruit oil at 27th, which is a botanical rather than a compounded fragrance — worth knowing if you avoid fragrance for sensitivity reasons, because a botanical oil can still be a trigger. Preservation is handled by 1,2-hexanediol (5th), ethylhexylglycerin (13th) and pentylene glycol (52nd), so there is no paraben and no phenoxyethanol in this formula.

The supporting cast

Beyond the headliners, the Hyaluronic Multi Peptide PDRN Serum carries trehalose (7th), glyceryl glucoside (8th) and sorbitol (9th) as additional humectants, glucose at 17th, and a run of botanical extracts: neem leaf and flower (18th and 19th), ivy gourd fruit (23rd), eggplant fruit (24th), aloe flower (26th), holy basil leaf (29th), coralline algae (31st) and turmeric root (32nd). Collagen extract sits at 36th, in among the peptides. Disodium EDTA at 16th is a chelator that keeps the formula stable.

Size and value of the Hyaluronic Multi Peptide PDRN Serum

At 30ml with a dropper, two to three drops per use puts this at roughly two to three months of once-daily use, or about six weeks used twice daily. That is the normal working life of a 30ml serum. Store it properly and use it within twelve months of opening.

A simple routine that works

Morning: gentle cleanser, then two to three drops of the Hyaluronic Multi Peptide PDRN Serum patted into slightly damp skin, then a light gel moisturiser, then broad-spectrum sunscreen. Evening: cleanse, serum, cream. That is it. You do not need a ten-step routine for this to work, and adding four more actives around it mostly increases the chance of irritation rather than results.

If you are already using a vitamin C serum in the morning, put the vitamin C on first, let it settle for a minute, then layer this over it. If you use an exfoliating acid, keep it to two or three nights a week and skip it on the nights your skin feels tight.

How to patch test properly

Apply a small amount to the inside of your forearm once a day for three days running. Leave it on and do not wash the area for at least twelve hours each time. Watch for redness, itching, small bumps or a burning sensation. If nothing happens by day four, move to a small patch beside your jaw for two more days before using it on your whole face. This matters more than usual here because of the bergamot oil.

Reading an ingredient list yourself

Two rules cover most of it. First, ingredients are listed heaviest to lightest until you reach 1% of the formula, after which the order is at the manufacturer’s discretion. Second, the 1% line usually sits somewhere around the first preservative or the first thickener that appears low on the list. Everything after that point is present in small amounts. Applied here, that puts the peptide block, the collagen extract and six of the eight hyaluronic acid derivatives well below 1% each.

That is not a criticism of the formula. Plenty of ingredients are effective below 1%, and adenosine, the Korean functional anti-wrinkle ingredient at 15th, is regulated at a fraction of a percent. It just means you should buy this for the top ten ingredients, not for the marketing on the box.

What comes in the box

One 30ml glass bottle with a rubber-bulb dropper, in a printed outer carton. The dropper is the standard MEDICUBE fitting and draws cleanly once the bottle has been shaken. Nothing else is included.

Honest summary

The Hyaluronic Multi Peptide PDRN Serum is a well-built, multi-purpose hydrating serum with a genuinely broad ingredient deck and two figures on the label that hold up when you check them. Its strengths are the niacinamide at 6th, the 0.5% sodium hyaluronate at 10th and a comfortable dual-phase texture. Its limitations are that the 13 peptides and six of the eight hyaluronic acid forms sit in the bottom half of the list, and that the bergamot grade is unstated. If you want a daily hydrator that plays well with everything else on your shelf, it is a sound buy. If you want a high-percentage single-active treatment, buy something else.

Authenticity

This Hyaluronic Multi Peptide PDRN Serum is authentic MEDICUBE stock. Product photography on this page is MEDICUBE’s own official imagery. We have excluded the brand’s before-and-after graphic and its moisture-percentage claim slide, because we do not republish results claims we cannot verify.

Other MEDICUBE serums we stock

If this one is not the right fit, compare it with the MEDICUBE TXA Niacinamide 15% Serum 30ml for tone, the MEDICUBE Ultra Light PDRN Serum for a lighter finish, or the MEDICUBE Kojic Acid Turmeric Serum for dark spots. The full ingredient list is published on MEDICUBE’s official product page, and the furocoumarin limits referenced above sit in EU Cosmetics Regulation 1223/2009.

Delivery across Bangladesh

Frequently asked questions

Do I really have to shake it every time? Yes. The two phases separate within minutes of standing. An unshaken pipette pull gives you the wrong ratio.

Can I use the Hyaluronic Multi Peptide PDRN Serum morning and night? Yes. Use sunscreen in the morning regardless.

Is it fragrance-free? There is no added parfum, but bergamot fruit oil at 27th gives it a scent. It is not fragrance-free in the sense a sensitive-skin user means.

Will the Hyaluronic Multi Peptide PDRN Serum make me oily? Two to three drops, patted in, should not. Overapplying an oil-phase serum will.

Can I use it with my acne treatment? Space them out rather than layering directly, and check with your dermatologist if you are on a prescription.

Does the peptide count matter if they are at the bottom of the list? Peptides work at low percentages, so being low on the list is not disqualifying. But 13 peptides at 33rd to 46th is a blend, not a high-dose peptide treatment. Buy it for the hydration and the niacinamide; treat the peptides as a bonus.

Is this the same as the capsule creams? No. The Hyaluronic Multi Peptide PDRN Serum is a dual-layer liquid serum in a dropper bottle. The capsule creams are separate products with their own formulas — see the MEDICUBE Hyaluronic Capsule Cream 55g and the MEDICUBE Collagen Capsule Cream.

What is the shelf life of the Hyaluronic Multi Peptide PDRN Serum? Use within twelve months of opening, stored at room temperature away from sunlight.